Table 3.

Univariate and multivariate analysis for overall survival.

Variable	Univariate analysis		Multivariate analysis
	Hazard ratio (95% CI)	p value	Hazard ratio (95% CI)	p value
T category (T1 vs. T2 vs. T3 vs. T4)	2.2 (1.01–4.793)	0.041	1.709 (0.71–4.115)	0.232
N category (N0 vs. N1 vs. N2)	2.46 (1.176–5.127)	0.006	1.951 (0.89–4.278)	0.105
M category (M0 vs. M1)	6.073 (2.221–16.603)	< 0.001	4.278 (1.507–12.146)	0.006
BRAF mutations (mutant vs. wild type)	1.391 (0.5–3.873)	0.528
TP53 mutations (mutant vs. wild type)	0.596 (0.234–1.518)	0.278
RB1 alterations (alteration vs. wild type)	1.898 (0.784–4.594)	0.155

CI confidence interval.