Table 1.
Demographics and clinical summary.
| Characteristic | Participants | Controls | P-value |
|---|---|---|---|
| n | 53 | 36 | |
| Sex | 17 F, 36 M | 22 F, 14 M | 0.013 |
| Mean Age (SD) | 51.2 (17.3) | 49.4 (15.0) | 0.54 |
| Handedness | 3 L, 47 R, 3 unk | 6 L, 27 R, 3 unk | 0.19 |
| Education | 0.35 | ||
| High school | 10 | 6 | |
| Some college | 11 | 7 | |
| Bachelors | 11 | 13 | |
| Graduate | 6 | 4 | |
| Unk | 15 | 6 | |
| Tumor Laterality | 49 L, 4 R | 1 L, 35 R | 3.6 × 10–16 |
| Tumor Grade/Pathology | 0.18 | ||
| WHO Grade I—II | 11 | 9 | |
| WHO Grade III | 15 | 4 | |
| WHO Grade IV | 24 | 23 | |
| Metastasis | 3 | 0 |
Comparisons between categorical variables were made with the chi-squared test while continuous variables were compared with the Wilcoxon rank-sum test for participants with dominant hemisphere lesions and controls with non-dominant hemisphere lesions. Handedness was determined using preoperative magnetoencephalography. Education was self-reported in patients who completed the Neuro-QoL assessment. Pathologic diagnoses were made by board-certified pathologists using the World Health Organization (WHO) Revised Classification of Tumors in the CNS. Unk.-Unknown.