Perfusion and diffusion MR parameter ratios for infarct core (region 1), penumbra that infarcts (region 2), and hypoperfused tissue that recovers (region 3)
| Parameter | Region 1 | Region 2 | Region 3 | P Value* |
|---|---|---|---|---|
| Perfusion | ||||
| rCBF | 0.32 ± 0.11 | 0.46 ± 0.13 | 0.58 ± 0.12 | <.001 |
| (0.16–0.61) | (0.24–0.79) | (0.36–0.84) | ||
| rCBV | 0.56 ± 0.21 | 0.80 ± 0.25 | 0.91 ± 0.18 | .056 |
| (0.16–0.88) | (0.43–1.44) | (0.53–1.21) | ||
| MTT | 1.70 ± 0.42 | 1.74 ± 0.42 | 1.65 ± 0.43 | .484 |
| (0.93–2.70) | (0.89–2.62) | (0.65–2.70) | ||
| Diffusion | ||||
| ADC | 0.63 ± 0.12 | 0.90 ± 0.11 | 0.96 ± 0.05 | .018 |
| (0.45–0.93) | (0.69–1.12) | (0.85–1.06) | ||
| DWI | 1.84 ± 0.41 | 1.13 ± 0.08 | 1.08 ± 0.07 | .014 |
| (1.07–2.71) | (1.02–1.34) | (0.95–1.22) | ||
| FA | 1.13 ± 0.20 | 1.02 ± 0.10 | 1.02 ± 0.06 | .862 |
| (0.83–1.64) | (0.84–1.18) | (0.92–1.10) |
Note.—DWI indicates DW image signal intensity. Data are mean ratios ± SD.
Numbers in parentheses are the range.
*
P values are for the comparison between region 2 and region 3.