Figure 1.

Cellular metabolism of glucose. The figure shows relevant steps in metabolization of glucose following uptake from the extracellular milieu. Red circles indicate the analyzed amino acids, i.e. alanine (Ala), aspartate (Asp), glutamate (Glu), proline (Pro), serine (Ser), and glycine (Gly), with regard to enrichment of ¹³C in mock-treated controls and cells incubated with ²¹³Bi-anti-EGFR-MAb. Results of ¹³C-enrichment in EJ28Luc bladder cancer cells. Red arrows indicate significantly decreased enrichment of ¹³C in ²¹³Bi-anti-EGFR-MAb treated cells compared to controls. ETC electron transport chain; (adapted from⁴).