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. 2021 Mar 18;11:6226. doi: 10.1038/s41598-021-85618-3

Table 3.

Procedural details.

RSPV RIPV
PNP (−) n = 486 PNP (+) n = 20 P PNP (−) n = 486 PNP (+) n = 9 P
4th generation cryoballoon 23 (4.7%) 1 (5.0%) 0.96 23 (4.8%) 2 (25%) 0.07
No. of freezing 1.4 ± 0.6 1.1 ± 0.4 0.001 1.5 ± 0.8 1.1 ± 0.3 0.13
Time to − 30 °C 26.5 ± 5.3 26.8 ± 3.5 0.81 31.7 ± 9.8 31.1 ± 4.9 0.76
Time to − 40 °C 43.7 ± 13.0 45.0 ± 10.5 0.71 62.0 ± 35.1 52.9 ± 13.9 0.17
Time to isolation (sec) 34.0 ± 22.5 31.2 ± 18.8 0.56 45.5 ± 30.3 68.5 ± 16.3 0.29
Total freezing time (sec) 220 ± 76 151 ± 64  < 0.001 233 ± 101 144 ± 45  < 0.001
Nadir balloon temperature (°C)  − 54.4 ± 5.5  − 52.3 ± 3.8 0.12  − 49.0 ± 7.6  − 48.1 ± 6.2 0.67
Circumferential length of PV ostium (mm) 59.3 ± 12.3 63.5 ± 17.1 0.35 53.4 ± 12.0 49.9 ± 6.7 0.16
Length of PV trunk (mm) 18.9 ± 7.1 19.0 ± 6.8 0.97 13.0 ± 5.1 11.9± 3.6 0.38
The order of PVI (RIPV → RSPV) 131 (28%) 6 (30%) 0.76 133 (27%) 4 (44%) 0.27
Phrenic nerve pacing for CMAP recording
Pacing from the subclavian vein 409 (84%) 19 (95%) 0.18 411 (85%) 8 (89%) 0.72
Paced by the circular catheter 138 (28%) 8 (40%) 0.26 141 (29%) 7 (78%) 0.004
Pacing threshold (V) 2.9 ± 1.6 2.2 ± 0.9 0.09 2.9 ± 1.6 2.5 ± 0.7 0.62
Maximum CMAP reduction (%) 3.0 ± 21.1 39.1 ± 40.6 0.01 0.8 ± 22.8 36.6 ± 48.0 0.008

The data are presented as the mean ± standard deviation.

Abbreviations are the same as in the previous table.