Table 1.
Comparison of hospitalized COVID-19 patients with or without vitamin D deficiency (VDD), data presented as number (percentage) for categoricala and mean (SD) for continuous variablesb.
| Parameter | No VDD (n = 212) | VDD (n = 197) | P-value |
|---|---|---|---|
| Age (years)b | 57.8 (14.7) | 46.7 (17.1) | < 0.001 |
| Femalesa | 64 (30.2) | 63 (32) | 0.70 |
| BMI, kg/m2 (n = 136) | 27.5 (4.8) | 27.2 (4.3) | 0.67 |
| Systolic BP (mm of Hg)b | 129.8 (14.8) | 128.8 (14.9) | 0.48 |
| Diastolic BP (mm of Hg)b | 78.7 (10) | 77.4 (9.7) | 0.19 |
| Comorbiditiesa | 161 (75.9) | 110 (55.8) | < 0.001 |
| Diabetesa | 111 (52.4) | 77 (39.1) | 0.01 |
| Hypertensiona | 105 (49.5) | 58 (29.4) | < 0.001 |
| CADa | 18 (8.5) | 16 (8.1) | 0.89 |
| CKDa | 6 (2.8) | 6 (3) | 0.90 |
| Hypothyroidisma | 38 (17.9) | 23 (11.7) | 0.08 |
| Cancera | 8 (3.8) | 3 (1.5) | 0.16 |
| Respiratory diseasea | 14 (6.6) | 10 (5.1) | 0.51 |
| Symptomatic casesa | 206 (97.2) | 186 (94.4) | 0.16 |
| Duration of symptomsb (days) | 5.8 (3.3) | 5.7 (3.2) | 0.67 |
| Baseline SpO2 (mm of Hg)b | 95.6 (3.5) | 95.7 (4.6) | 0.84 |
| Baseline severity scoresb | 3.3 (0.6) | 3.3 (0.6) | 0.68 |
| Hospital stay (d)b | 10 (5.8) | 9.2 (5.6) | 0.13 |
| Outcome severity scoreb | 3.7 (1.2) | 3.6 (1) | 0.12 |
| Severe casesa | 31 (14.6) | 26 (13.2) | 0.78 |
| Oxygena | 92 (43.4) | 68 (34.5) | 0.07 |
| ICU admissiona | 42 (19.8) | 29 (14.7) | 0.17 |
| RRTa | 6 (2.8) | 1 (0.5) | 0.07 |
| Inotropic supporta | 12 (5.7) | 7 (3.6) | 0.31 |
| Mortalitya | 11 (5.2) | 4 (2.0) | 0.12 |
| 25-OHD (ng/mL)b | 43.2 (25.8) | 9.8 (5) | < 0.001 |
| PTH (pg/mL)b | 47.5 (42.9) | 63.5 (54.4) | 0.001 |
| Albumin correctedb calcium (mg/dL) | 9.2 (1.2) | 9 (0.5) | 0.02 |
| CRP (mg/L)b | 45.1 (56.0) | 62.2 (343.7) | 0.49 |
| IL-6 (pg/mL)b | 45.9 (121) | 46.3 (113.5) | 0.98 |
| LDH (IU/L)b | 301.1 (123.5) | 304 (129.3) | 0.83 |
| D-Dimer (ng/mL)b | 310.8 (722.6) | 465.3 (1646.2) | 0.22 |
| Ferritin (ng/mL)b | 311.1 (514.2) | 332.7 (618.7) | 0.71 |