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. 2021 Mar 18;11:6254. doi: 10.1038/s41598-021-82602-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The stability, biocompatibility and photothermal effect of IR780-NBs-DTX. (a,b) Changes in the size distribution and concentration of IR780-NBs-DTX over 80 min. ^#P < 0.05, significantly different from the size distribution at 5 min; ^&P < 0.05, significantly different from the concentration at 5 min. (c) The cytotoxicity of IR780-NBs-DTX at different concentrations (0: control cells; 6 × 10⁵/mL; 6 × 10⁶/mL; 6 × 10⁷/mL; 6 × 10⁸/mL; 6 × 10⁹/mL; 6 × 10¹⁰/mL). *P < 0.05, significantly different from the cytotoxicity in control cells. (d) The photothermal effect of IR780-NBs-DTX under an 808 nm laser at different intensities.