Table 1.

The EE and DL of IR-780 iodide and DTX in IR780-NBs-DTX with different initial doses.

Drug	Initial adding dose (mg)	EE	DL
IR-780 iodide	0.05	51.6 ± 1.2%	0.37 ± 0.06%
	0.10	61.5 ± 0.9%¥	0.88 ± 0.09%
	0.15	60.4 ± 0.5%	1.29 ± 0.55%#
DTX	0.05	23.8 ± 2.1%	1.7 ± 0.2%
	0.10	32.5 ± 1.9%&,^	4.6 ± 0.9%*
	0.15	22.9 ± 3.2%	4.9 ± 0.7%

^#P < 0.05, significantly different from the DL of IR-780 iodide with an initial dose of 0.05 mg. ^¥P < 0.05, significantly different from the EE of IR-780 iodide with an initial dose of 0.05 mg. *P < 0.05, significantly different from the DL of DTX with an initial dose of 0.5 mg. ^&P < 0.05, significantly different from the EE of DTX with an initial dose of 0.5 mg. ^{^}P < 0.05, significantly different from the EE of DTX with an initial dose of 1.5 mg. Data are presented as the mean ± standard deviation.