Table 5.
Descriptive analysis of demographic and clinical characteristics by region. All patients.
| Demographic and clinical characteristics stratified by region | ||
|---|---|---|
| Valencia (n = 259) | Catalonia (n = 591) | |
| Variables | ||
| Sex [n (%)] | ||
| Women | 109 (42.1) | 263 (44.5) |
| Men | 150 (57.9) | 328 (55.5) |
| Age et al. diagnosisa | 62.43 (11.67) | 63.51 (12.54) |
| 63 (56.0–70.0) | 65.0 (56.0–73.0) | |
| (21–86) | (25–89) | |
| Age at diagnosis in quintiles [n (%)] | ||
| < = 53/ < = 52 | 45 (17.4) | 106 (17.9) |
| (53–59]/(52–61] | 57 (22.0) | 117 (19.8) |
| (59–66]/(61,67] | 49 (18.9) | 122 (20.6) |
| (66–71]/(67,74.6] | 55 (21.2) | 121 (20.5) |
| > 71/ > 74.6 | 53 (20.5) | 125 (21.2) |
| Definite diagnosis [n (%)] | ||
| ALS | 219 (85.5) | 524 (96.7) |
| PMA | 27 (10.5) | 14 (2.6) |
| PLS | 10 (3.9) | 4 (0.7) |
| Symptom at onset [n (%)] | ||
| Bulbar | 62 (28.31) | 155 (29.58) |
| Spinal | 146 (66.67) | 336 (64.12) |
| Respiratory | 4 (1.83) | 20 (3.82) |
| Cognitive (dementia) | 7 (3.20) | 13 (2.48) |
| C9orf72 [n (%)] | 17 (6.94) (n = 245) | 33 (7.67) (n = 430) |
| SOD1 [n (%)] | 8 (3.27) (n = 245) | 3 (2.22) (n = 135) |
ALS Amyotrophic Lateral Sclerosis, PMA Progressive Muscular Atrophy, PLS Primary Lateral Sclerosis.
aFirst row: mean (sd).
Second row: median (1st-3rd quartiles).
Third row: (min–max).