. 2021 Mar 18;11:6224. doi: 10.1038/s41598-021-85772-8

Table 3.

IC₅₀ (µg/ml) of different extracts of Annona b. and Annona h. against proliferation of human cancer cell lines.

Cells	Annona b.			Annona h.
Cells	Peel	Pulp	Seed	Peel	Pulp	Seed
Caco-2	30.69 ± 0.35^b	45.05 ± 5.80^b	11.55 ± 1.04 ^a	44.68 ± 2.80^b	34.24 ± 1.60^b	12.81 ± 0.02^a
HepG-2	15.28 ± 0.67^b	27.56 ± 2.10^c	7.99 ± 0.21^a	> 200	> 200	10.21 ± 1.78^a
MCF-7	15.17 ± 0.17^a	27.82 ± 5.50^b	14.34 ± 0.35^a	> 200	42.39 ± 0.64^c	15.99 ± 1.25^a
PC-3	14.36 ± 0.35^b	22.65 ± 1.32^c	7.31 ± 0.03^a	> 200	> 200	10.96 ± 0.64^a

Results are presented as Mean ± SE (n = 3). Different letters in the same row are significantly different at p < 0.05; IC50, concentration of the studied extracts that caused 50% viability for tested cells.