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. 2021 Mar 18;11:6211. doi: 10.1038/s41598-021-85614-7

Table 4.

Multivariate analysis using modified least squares regression.

Parameter Reference Risk difference 95% CI P
PVI ACHX 12.9 8.8–16.9  < 0.001
CV Other Venous 17.3 3.6–31.0 0.013
Femoral Venous 13.1 8.2–17.9  < 0.001
Male Female 2.3 -3.4–8 0.425
Age per 10 years 1.8 0.3–3.2 0.015
Antiseptics and blood sampling sites
PVI/CV Other ACHX/Femoral 24.5 9.7–67.8 0.004
PVI/Femoral ACHX/Femoral 20.3 13.5–27.0  < 0.001
PVI/Venous ACHX/Femoral 2.2 −2.6 to 7.1 0.362
ACHX/CV Other ACHX/Femoral 1.7 −2.6 to 6.0 0.444
ACHX/Venous ACHX/Femoral −1.1 −4.6 to 2.3 0.524
Male Female 2.2 −3.5 to 7.9 0.447
Age per 10 years 1.7 0.2–3.1 0.028

ACHX, 1.0% alcohol/chlorhexidine gluconate; CI confidence interval, CV Other, blood culture sample from recently inserted central venous, venous and arterial catheters, implanted port; Femoral, femoral artery or vein; PVI, 10% aqueous povidone-iodine; Venous, venipuncture without catheter insertion.