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. 2021 Mar 18;11:6328. doi: 10.1038/s41598-021-85948-2

Table 3.

Multivariable analysis of time to treatment failure and overall survival (Cox hazard model).

Variable TTF OS
HR 95% CI P HR 95% CI P
ALC > 1500/μL versus ALC ≤ 1500/μL 0.53 0.32–0.88 0.013 0.44 0.23–0.82 0.010
NLR ≤ 3 versus NLR > 3 0.63 0.43–0.94 0.023 0.62 0.39–0.99 0.045
PLR ≤ 300 versus PLR > 300 0.51 0.33–0.81 0.004 0.63 0.38–1.02 0.062
LMR > 3 versus LMR ≤ 3 0.70 0.47–1.03 0.069 0.60 0.38–0.96 0.034

ALC absolute lymphocyte count, CI confidence interval, HR hazard ratio, LMR lymphocyte-to-monocyte ratio, NLR neutrophil-to-lymphocyte ratio, OS overall survival, PLR platelet-to-lymphocyte ratio, TTF time to treatment failure.