. 2021 Mar 18;11:6231. doi: 10.1038/s41598-021-85670-z

Table 2.

Influence of background factors of the mother and child at 1 month on occupancies of the five most dominant bacterial genera in the intestinal microbiome of the infant.

Variances	Bifidobacterium				Streptococcus			Bacteroides				Clostridium				Escherichia
Variances	Odds Ratio	95% CI			Odds Ratio	95% CI		Odds Ratio	95% CI			Odds Ratio	95% CI			Odds Ratio	95% CI
Gestational days^a
1	0.96	0.91	1.02		1.05	0.99	1.11	0.93	0.87	0.98	*	1.09	1.03	1.14	**	0.92	0.87	0.98	**
2	1.03	0.97	1.09		1.03	0.98	1.09	0.89	0.83	0.94	**	1.06	1.002	1.13	*	0.93	0.88	0.99	*
3	0.95	0.90	1.00		1.01	0.96	1.07	1.00	0.95	1.07		1.03	0.97	1.10		0.96	0.91	1.02
Birth weight^a
1	0.999	0.998	1.00		1.001	0.99	1.002	0.999	0.998	1.00		1.002	1.00	1.003		0.998	0.996	0.999	**
2	0.999	0.998	1.00		1.001	0.99	1.002	0.998	0.99	1.00		1.001	1.00	1.003		0.998	0.99	1.00
3	0.999	0.998	1.00		0.999	0.99	1.001	0.999	0.99	1.00		1.001	1.00	1.003		0.999	0.998	1.001
Age of mothers^a
1	1.00	0.91	1.11		1.02	0.93	1.13	1.09	0.94	1.14		0.91	0.83	0.99	*	1.07	0.97	1.18
2	0.96	0.87	1.06		1.00	0.91	1.11	1.03	0.94	1.14		0.94	0.85	1.04		1.13	1.02	1.25
3	0.98	0.89	1.08		1.03	0.94	1.14	1.10	1.00	1.21		0.96	0.86	1.07		1.05	0.96	1.16
Male	1.47	0.57	3.75		1.20	0.57	2.53	1.35	0.56	3.23		0.85	0.33	2.18		1.45	0.67	3.14
Vaginal delivery	1.84	0.49	6.92		1.06	0.32	3.54	0.026	0.003	0.23	**	4.94	1.10	22.23	*	0.48	0.14	1.68
Infants without siblings	3.03	1.09	8.43	*	1.19	0.56	2.57	0.96	0.40	2.33		0.22	0.072	0.66	**	0.84	0.38	1.87
Non-AED	0.11	0.03	0.39	***	1.22	0.53	2.82	0.65	0.27	1.56		4.98	1.69	14.69	**	0.75	0.32	1.77
Mothers without allergy	1.33	0.51	3.50		1.27	0.60	2.72	1.14	0.46	2.78		0.85	0.33	2.23		1.62	0.73	3.58
Exclusively breast-fed	1.06	0.41	2.73		2.06	0.96	4.41	1.61	0.66	3.94		5.88	2.24	15.43	***	0.97	0.44	2.13

The bacterial genera are shown from left to right in the order of higher occupancy (mean). For the continuous variables (^a gestational age at birth, birth weight, and maternal age), occupancy was classified from 1 to 4 in ascending order from low occupancy with the occupancy of each bacterial species rounded to four decimal places. For the high occupancy group (group 4), a multinomial logistic regression analysis was performed as the category standard and the occupancy was classified into two groups based on the median for each genus for the logistic regression analysis for categorical variables. The odds ratio and 95% confidence interval were calculated using the logistic regression analysis and the multinomial regression analysis. The significance level was set at 5%. *p < 0.05, **p < 0.01, ***p < 0.001.