Photomicrographs of sections stained with hematoxylin-eosin.
A, Low-power view of the cerebellum shows leptomeningeal infiltrate and superficial cortical tumor invasion (arrow) with cystic rarefaction (c) of deep white matter by tumor.
B, Medium-power view of area of cortical tumor invasion shown in A reveals neoplastic cells (T) in a rarefied area of cortex.
C, The leptomeningeal infiltrate is composed of a monomorphous population of noncohesive cells with interspersed eosinophilic granular bodies (straight arrow) and marked fibrous proliferation (curved arrows).
D, View of spinal cord lesion shows an isolated anterior horn neuron (arrow) in a background of tumor cells.