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. 2019 Dec 30;9(6):671–679. doi: 10.1093/jpids/piz094

Table 7.

Clinical Outcomes for Tracheostomy Patient Subpopulation by Overall Serum-Associated Antibiotic Tolerance (SAT) Status and SAT Pharmacologic Phenotype

Outcome SAT-Negative (n = 4) SAT-Positive (n = 10) P Value Minocycline SAT-Positive (n = 7) P Value Tobramycin SAT-Positive (n = 5) P Value
Duration with fever, median (IQR), d 1.0 (0.5, 4.0) 0.0 (0.0, 0.0) .21 0.0 (0.0, 0.0) .21 0.0 (0.0, 1.0) .63
Duration in pediatric intensive care unit, median (IQR), d 1.0 (0.0, 2.0) 0.5 (0.0, 3.0) .83 0.0 (0.0, 3.0) .82 1.0 (0.0, 19.0) .73
Hospital length of stay, median (IQR), d 6.0 (4.5, 39.0) 5.5 (3.0, 11.0) .73 6.0 (5.0, 11.0) .94 11.0 (2.0, 18.0) .90
Duration of antibiotics, median (IQR), d 6.0 (4.0, 8.0) 3.0 (0.0, 9.0) .56 3.0 (3.0, 9.0) .74 9.0 (3.0, 10.0) .72
Duration of oxygen therapy (>home requirement), median (IQR), d 6.5 (4.5, 10.0) 6.0 (4.0, 9.0) 1.0 6.0 (6.0, 9.0) .85 9.0 (3.0, 11.0) 1.0
Mortality, n (%) 0 (0.0) 1 (10.0) 1.0 1 (11.1) 1.0 1 (20) 1.0

Abbreviation: IQR, interquartile range; SAT, serum-associated antibiotic tolerance.