Table:
Clinical information and 1H MR spectroscopic findings in 15 patients with pyogenic brain abscesses
| Patient No./Sex/ Age (y) | Chief Complaint | Location of Abscess | Pus Culture Microorganisms | Treatment | Outcome | Duration of Symptoms | MR Spectroscopy before/after Starting Antibiotics | MR Spectroscopic Findings |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pattern | NAA | Cr | Cho | Succ | Ace | Ala | AA | Lac | Lip | ||||||||
| 1/F/45 | Fever, headache, unstable gait | Left cerebellum | Bacteroides fragilis | Surgery/medical | Cured | 10 days | 1 day after | A | + | + | ++ | ++ | +++ | ++ | ++ | +++ | ++ |
| 2/M/74 | Right hemiparesis | Left parietal | Streptococcus intermedius | Surgery/medical | Cured | 30 days | 1 day before | A | − | − | − | − | + | + | ++ | ++ | − |
| 3/M/69 | Fever, right hemiparesis | Left parietal | B fragilis | Surgery/medical | Died | 7 days | 1 day before | A | + | + | + | ++ | +++ | + | ++ | ++ | + |
| 4/M/48 | Headache | Left frontal | Negative | Surgery/medical | Cured | 10 days | 2 days before | A | − | − | − | − | +++ | ++ | +++ | +++ | + |
| 5/M/45 | Fever, headache | Right temporal | Streptococcus mitis, Enterococcus faecalis | Surgery/medical | Cured | 12 days | 2 days after | A | − | − | − | ++ | ++ | + | +++ | +++ | − |
| 6/M/43 | Consciousness change | Right basal ganglion | Eubacterium lentum | Surgery/medical | Cured | 3 days | 1 day after | A | − | − | − | ++ | ++ | ++ | ++ | +++ | − |
| 7/M/47 | Headache, left homonymous hemianopia | Right occipital | S intermedius | Surgery/medical | Cured | 14 days | 1 day after | B | − | − | − | − | − | − | + | ++ | − |
| 8/F/28 | Right homonymous hemianopia | Left occipital | S intermedius | Surgery/medical | Cured | 21 days | 2 days before | B | − | − | − | − | − | − | + | ++ | − |
| 9/M/76 | Fever, consciousness change | Left temporal | Negative | Surgery/medical | Cured | 14 days | 1 day after | B | + | + | + | − | − | − | + | ++ | − |
| 10/F/69 | Left hemiparesis | Right frontal | Staphylococcus aureus | Surgery/medical | Cured | 3 days | 1 day before | B | + | + | + | − | − | − | + | ++ | − |
| 11/F/29 | Fever, headache | Left frontal | Pseudomonas aeruginosa | Surgery/medical | Cured | 2 wks | 2 days after | B | − | − | − | − | − | − | + | ++ | + |
| 12/M/72 | Fever, left hemiparesis | Right parietal | S intermedius | Surgery/medical | Cured | 10 days | 2 days before | B | + | + | + | − | − | − | + | ++ | − |
| 13/M/72 | Left hemiparesis, infective endocarditis | Multiple | Streptococcus constellatus | Surgery/medical | Died | 30 days | 1 day after | B | − | − | − | − | − | − | + | ++ | − |
| 14/F/78 | Fever, consciousness change | Right temporal | P aeruginosa | Surgery/medical | Cured | 10 days | 2 days after | B | − | − | − | − | − | − | + | ++ | − |
| 15/M/72 | Consciousnes change, infective endocarditis | Multiple military (<5 mm) | S mitis (blood culture) | Medical | Cured | 3 days | 1 day after | C | ++ | + | ++ | − | − | − | − | + | − |
Notes.—Negative sign indicates no bacterial growth; +, small peak; ++, moderate peak; +++, large peak; Ace, acetate; Ala, alanine; AA, amino acids; Lac, lactate; Succ, succinate; NAA, N-acetylaspartate; Cho, choline; Cr, creatine-phosphocreatine; Lip, lipids.