Summary of Relevant Clinical and Angiographic Data and Outcomes in 29 Patients with 31 Very Large or Giant Aneurysms
| Patient No./Sex/Age (y) | Clinical Presentation | Aneurysm Location and Size | Timing of Tx after SAH | Initial Occlusion | Complications of Initial Coiling | Occlusion at First Follow-Up | Complications | Additional Tx after Coiling | Occlusion at Last Follow-Up* | Final Occlusion† | Clinical Result in Non-SAH Patients | GOS Score in SAH Patients |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1/F/49 | 1) ME, ophthalmoplegia and 2) AA | 1) Carotid cavernous sinus, 35 mm, and 2) carotid ophthalmic, 20 mm | NA | 1) Incomplete and 2) near complete | None | Complete at 5 mo | None | None | Complete at 15 mo | NA | Ophthalmoplegia improved at 64 mo | NA |
| 2/M/46 | AA, SAH | Basilar tip, 20 mm | NA | Complete | None | Incomplete at 10 mo | None | Repeat coiling | Complete at 16 mo | NA | Asymptomatic at 55 mo | NA |
| 3/F/35 | ME, decreased visual acuity | Carotid bifurcation, 40 mm | NA | Incomplete | None | Incomplete at 3 mo | Hemiparesis | Carotid balloon occlusion | Incomplete at 3 mo | Complete at 6 mo | Died of pneumonia after SAH from AA at 14 mo | NA |
| 4/F/65 | SAH H&H II | Carotid hypophyseal, 35 mm | 29 d | Complete | None | Incomplete at 11 mo | None | Repeat coiling | Near complete at 22 mo | NA | NA | 5 at 52 mo |
| 5/M/48 | ME, mutism, hemiplegia | Carotid bifurcation, 55 mm | NA | Complete | None | Incomplete at 11 mo | None | Repeat coiling, carotid balloon occlusion | Incomplete at 11 mo | Complete at 21 mo | Improved at 51 mo | NA |
| 6/M/52 | SAH H&H II | Basilar tip, 28 mm | 16 d | Incomplete | None | Incomplete at 2 mo | Brainstem compression and edema, fatal rebleed | Bypass surgery to P2, bilateral vertebral occlusion | Incomplete at 3 mo | Incomplete at 3 mo | NA | 1 at 6 mo, fatal rebleed |
| 7/M/68 | SAH H&H II | Basilar tip, 26 mm | 15 d | Incomplete | None | Complete at 3 mo | Hydrocephalus, VP shunt | None | Complete at 3 mo | NA | NA | 5 at 49 mo |
| 8/F/56 | ME, ataxia, facial palsy | PICA, 32 mm | NA | Near complete | None | Incomplete at 8 mo | None | Repeat coiling | Complete at 46 mo | NA | Asymptomatic at 48 mo | NA |
| 9/F/51 | ME, visual loss, ophthalmoplegia | Carotid ophthalmic, 35 mm | NA | Incomplete | None | Incomplete at 5 wk | None | Bypass surgery | Incomplete at 5 wk | Complete | Unchanged at 47 mo | NA |
| 10/F/63 | SAH H&H II | Basilar tip, 21 mm | 33 d | Complete | None | Complete at 10 mo | None | None | Complete at 10 mo | NA | NA | 5 at 49 mo |
| 11/M/40 | SAH H&H II | Basilar tip, 30 mm | 9 d | Complete | None | Incomplete at 10 mo | None | Repeat coiling | Complete at 33 mo | NA | NA | 5 at 45 mo |
| 12/F/41 | SAH H&H II | Supraclinoid carotid, 26 mm | 6 d | Near complete | None | Incomplete at 6 wk | None | Carotid balloon occlusion | Incomplete at 6 wk | Complete at 7 mo | NA | 5 at 45 mo |
| 13/M/57 | SAH H&H II | AcomA, 20 mm | 38 d | Incomplete | None | Incomplete at 7 mo | None | None | Incomplete at 20 mo | NA | NA | 5 at 38 mo |
| 14/F/50 | SAH H&H II | AcomA, 23 mm | 60 d | Complete | None | Incomplete at 6 mo | Transient hemiparesis | Repeat coiling | Complete at 21 mo | NA | NA | 5 at 33 mo |
| 15/M/67 | ME, trigeminal neuralgia | Superior cerebellar, 27 mm | NA | Complete | None | Incomplete at 6 mo | Aneurysm dissection, bypass surgery | Repeat coiling, bypass surgery | Incomplete at 6 mo | Complete at 10 mo | Improved at 36 mo | NA |
| 16/M/41 | SAH H&H II | AcomA, 20 mm | 22 d | Complete | TE event in A2 | Near-complete at 6 mo | None | None | Near complete at 17 mo | NA | NA | 5 at 31 mo |
| 17/M/61 | SAH H&H II | AcomA, 22 mm | 10 d | Near complete | None | Incomplete (at 10 months) | None | Repeat coiling, clipping | Incomplete at 10 mo | Complete | NA | 5 at 16 mo |
| 18/F/55 | SAH H&H II | Basilar tip, 20 mm | 7 d | Complete | None | Near complete at 8 mo | None | None | Near complete at 22 mo | NA | NA | 5 at 22 mo |
| 19/F/62 | SAH H&H IV | PcomA, 20 mm | 4 d | Complete | None | Incomplete at 6 mo | None | Repeat coiling | Near complete at 12 mo | NA | NA | 3 at 14 mo |
| 20/M/50 | SAH H&H II | Carotid bifurcation, 20 mm | 8 d | Complete | TE M1 occlusion, urokinase caused aneurysm rebleed | None | Death due to TE event and rebleed due to urokinase | None | NA | NA | NA | 1 at 1 d |
| 21/M/36 | SAH H&H I | AcomA, 24 mm | 21 d | Complete | None | Incomplete at 6 mo | None | None | Incomplete at 13 mo | NA | NA | 5 at 22 mo |
| 22/M/61 | ME, frontal syndrome, mutism | AcomA, 55 mm | NA | Complete | Transient paresis, R leg | None | None | None | None | NA | Death due to pneumonia at 3 mo | NA |
| 23/M/52 | ME, frontal syndrome | AcomA, 30 mm | NA | Incomplete | None | Incomplete at 6 mo | None | None | Incomplete at 13 mo | NA | Improved at 13 mo | NA |
| 24/F/47 | SAH H&H III | Basilar tip, 20 mm | 2 d | Complete | None | Complete at 6 mo | None | None | Complete at 12 mo | NA | NA | 5 at 18 mo |
| 25/F/43 | Incidental | Basilar tip, 26 mm | NA | Near complete | None | Incomplete at 6 mo | None | Repeat coiling | Near complete at 15 mo | NA | Asymptomatic at 15 mo | NA |
| 26/F/51 | 1) SAH H&H I and 2) AA | 1) L carotid bifurcation, 25 mm; 2) carotid bifurcation R, 25 mm | 1) 18 d and 2) NA | Near complete | None | Incomplete at 6 mo | 1) None and 2) massive infarction resulting in death after bypass surgery | 1) recoiling and 2) clipping | 1) Near complete at 6 mo and 2) incomplete at 6 mo | NA | 1) None and 2) death due to surgical complication at 16 mo | 1 at 16 mo |
| 27/F/54 | SAH H&H II | PcomA, 20 mm | 7 d | Complete | None | Near complete at 9 mo | None | None | Near complete at 40 mo | NA | NA | 5 at 40 mo |
| 28/F/60 | SAH H&H II | Basilar trunk, 30 mm | 7 d | Near complete | None | Incomplete at 7 mo | None | 2× repeat coiling | Complete at 17 mo | NA | NA | 5 at 17 mo |
| 29/M/32 | SAH H&H I | Carotid bifurcation, 20 mm | 7 d | Complete | Transient hemiparesis, aphasia | Complete at 6 mo | None | None | Complete at 6 mo | NA | NA | 5 at 6 mo |
Note.—AA indicates additional aneurysm; A2, second segment of the anterior cerebral artery; AcomA, anterior communicating artery; ME, mass effect; H&H, Hunt and Hess clinical grading at the time of treatment; NA, not applicable; PICA, posterior inferior cerebellar artery; TE, thromboembolic; Tx, treatment.
*
After coiling or repeat coiling.
†
After additional therapy other than coiling.