Table IV.
TGF-β1 and Smad4 expression in relation to clinicopathological findings in ESCC.
| Characteristics | Number (n=88) | TGF-β1 expression | P-value | Smad4 expression | P-value |
|---|---|---|---|---|---|
| Age (years) | 0.75848 | 0.69893 | |||
| >65 | 49 | 35 | 45 | ||
| ≤65 | 39 | 29 | 34 | ||
| Sex | 0.60701 | 0.75139 | |||
| Male | 66 | 49 | 60 | ||
| Female | 22 | 15 | 19 | ||
| Histological grade | 0.61817 | 0.56364 | |||
| Well diff. | 37 | 29 | 33 | ||
| Moderately diff. | 45 | 32 | 40 | ||
| Poorly diff. | 6 | 3 | 6 | ||
| Depth of invasion | 0.72166 | 0.7216 | |||
| Upper | 8 | 5 | 7 | ||
| Middle | 30 | 22 | 28 | ||
| Lower | 50 | 37 | 44 | ||
| Lymphatic invasion | 0.28511 | 0.41298 | |||
| Yes | 37 | 27 | 34 | ||
| No | 51 | 37 | 45 |
ESCC, esophageal squamous cell carcinoma; diff., differentiated.