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Serum levels of TNF-α, IFN-γ, IL-6 and IL-1β in each group at 6-h intervals as measured by ELISA assay. Serum (A) TNF-α, (B) IFN-γ, (C) IL-6 and (D) IL-1β levels. **P<0.01 as indicated. TNF, tumor necrosis factor; IFN, interferon; IL, interleukin; HS, hemorrhagic shock; MT, melatonin.
