Figure 6.

Breast-cancer-subtype-specific expression of cluster-signature genes

(A) Breast cancer gene expression data in TCGA (left) and METABRIC datasets were analyzed for enrichment of cluster-specific genes described in Table S3.

(B) PAM50 intrinsic subtype classifiers were used to subdivide breast cancers into luminal A, luminal B, HER2, basal, and claudin-low subtypes. Enrichment of cluster-specific genes in these subtypes of breast cancer were further analyzed.

(C) Kaplan-Meier curves show overall survival based on overlap in gene expression between specific clusters and specific subtypes of breast cancer. Additional data can be found in Figure S3.