Diffusion characteristics of five structures from both hemispheres in a patient with mild traumatic brain injury and a healthy control subject
Structure and Parameters | Patient |
Control Subject |
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Left Hemisphere | Right Hemisphere | P Value | Left Hemisphere | Right Hemisphere | P Value | |
Anterior corpus callosum | ||||||
λ1 | 1.50 ± 0.15 | 1.81 ± 0.25 | <0.005 | 1.84 ± 0.27 | 1.88 ± 0.21 | <0.4 |
λ2 | 0.67 ± 0.12 | 0.45 ± 0.11 | <0.005 | 0.43 ± 0.12 | 0.42 ± 0.09 | <0.4 |
λ3 | 0.37 ± 0.11 | 0.29 ± 0.08 | <0.005 | 0.20 ± 0.07 | 0.22 ± 0.07 | <0.3 |
Trace | 2.54 ± 0.21 | 2.55 ± 0.21 | ≈1 | 2.46 ± 0.21 | 2.52 ± 0.23 | <0.3 |
FA | 0.6 ± 0.09 | 0.76 ± 0.09 | <0.005 | 0.80 ± 0.08 | 0.81 ± 0.06 | <0.4 |
LI | 0.47 ± 0.10 | 0.65 ± 0.1 | <0.005 | 0.72 ± 0.11 | 0.72 ± 0.07 | <1 |
Posterior corpus callosum | ||||||
λ1 | 1.74 ± 0.27 | 1.64 ± 0.22 | <0.2 | 1.71 ± 0.12 | 1.62 ± 0.14 | <0.05 |
λ2 | 0.47 ± 0.15 | 0.49 ± 0.12 | <0.4 | 0.47 ± 0.10 | 0.45 ± 0.11 | <0.4 |
λ3 | 0.27 ± 0.10 | 0.24 ± 0.07 | <0.2 | 0.23 ± 0.08 | 0.16 ± 0.09 | <0.025 |
Trace | 2.49 ± 0.25 | 2.36 ± 0.19 | <0.1 | 2.41 ± 0.15 | 2.23 ± 0.19 | <0.005 |
FA | 0.75 ± 0.10 | 0.74 ± 0.08 | <0.4 | 0.77 ± 0.07 | 0.79 ± 0.07 | <0.3 |
LI | 0.65 ± 0.12 | 0.65 ± 0.09 | <1 | 0.69 ± 0.08 | 0.70 ± 0.08 | <0.4 |
External capsule | ||||||
λ1 | 1.28 ± 0.13 | 1.13 ± 0.13 | <0.005 | 1.26 ± 0.12 | 1.25 ± 0.11 | <0.5 |
λ2 | 0.69 ± 0.10 | 0.73 ± 0.10 | <0.1 | 0.65 ± 0.11 | 0.66 ± 0.08 | <0.4 |
λ3 | 0.37 ± 0.14 | 0.50 ± 0.10 | <0.005 | 0.34 ± 0.10 | 0.37 ± 0.05 | <0.2 |
Trace | 2.34 ± 0.14 | 2.36 ± 0.16 | <0.4 | 2.26 ± 0.19 | 2.28 ± 0.12 | <0.4 |
FA | 0.53 ± 0.10 | 0.39 ± 0.10 | <0.005 | 0.56 ± 0.08 | 0.53 ± 0.06 | <0.2 |
LI | 0.38 ± 0.09 | 0.26 ± 0.08 | <0.005 | 0.41 ± 0.08 | 0.37 ± 0.06 | <0.1 |
Posterior internal capsule | ||||||
λ1 | 1.23 ± 0.17 | 1.30 ± 0.16 | <0.1 | 1.42 ± 0.11 | 1.41 ± 0.12 | <0.5 |
λ2 | 0.64 ± 0.07 | 0.54 ± 0.11 | <0.005 | 0.49 ± 0.08 | 0.46 ± 0.07 | <0.2 |
λ3 | 0.36 ± 0.08 | 0.31 ± 0.04 | <0.01 | 0.25 ± 0.04 | 0.24 ± 0.07 | <0.4 |
Trace | 2.24 ± 0.17 | 2.14 ± 0.13 | <0.025 | 2.16 ± 0.09 | 2.12 ± 0.15 | <0.2 |
FA | 0.53 ± 0.09 | 0.63 ± 0.08 | <0.005 | 0.70 ± 0.06 | 0.71 ± 0.07 | <0.4 |
LI | 0.41 ± 0.09 | 0.50 ± 0.08 | <0.005 | 0.59 ± 0.06 | 0.60 ± 0.07 | <0.4 |
Anterior internal capsule | ||||||
λ1 | 1.24 ± 0.13 | 1.47 ± 0.06 | <0.005 | 1.38 ± 0.15 | 1.55 ± 0.23 | <0.025 |
λ2 | 0.59 ± 0.09 | 0.50 ± 0.09 | <0.01 | 0.56 ± 0.10 | 0.52 ± 0.10 | <0.2 |
λ3 | 0.42 ± 0.08 | 0.31 ± 0.06 | <0.005 | 0.33 ± 0.09 | 0.35 ± 0.10 | <0.3 |
Trace | 2.25 ± 0.13 | 2.29 ± 0.12 | <0.2 | 2.26 ± 0.24 | 2.41 ± 0.29 | <0.1 |
FA | 0.52 ± 0.09 | 0.68 ± 0.06 | <0.005 | 0.63 ± 0.05 | 0.67 ± 0.09 | <0.1 |
LI | 0.38 ± 0.09 | 0.56 ± 0.06 | <0.005 | 0.51 ± 0.06 | 0.55 ± 0.10 | <0.1 |
Note.—Data are the mean ± SD. The values of λ1, λ2, λ3, and trace were multiplied by 103 before they were included in the table and are in mm2/s.