fig 4.

Water-suppressed proton spectra of an 8-mL voxel located in the parietal region, recorded with a stimulated echo-based pulse sequence (1600/20; magnetization transfer, 30; number of acquisitions, 256). The main resonances correspond to N-acetylaspartate (2.0 ppm), glutamic/glutamine (2.1−2.5 ppm), creatine/phosphocreatine (3.02 ppm), choline-containing compounds (3.2 ppm), and myo-inositol (3.55 ppm). Comparison of the spectra shows a decrease in choline and myo-inositol resonances, with an increase in the glutamic/glutamine region in the cirrhotic patient.

A, Healthy control volunteer.

B, Cirrhotic patient.