Table 3.

Pharmacokinetic parameters of a single injection of BUP (n= 6) and BSR (n= 6) in common marmosets

	BUP	BSR
Cmax (ng/mL)	15.2 ± 8.10	2.78 ± 1.19
Tmax (h)	0.17 ± 0.13	4.42 ± 3.93
λz (1/h)	0.35 ± 0.12	0.02 ± 0.01
t1/2 (h)	2.23 ± 1.00	32.6 ± 9.57
AUC0-last (ng×h/mL)	16.1 ± 3.70	98.6 ± 42.7
AUC0-inf (ng×h/mL)	17.2 ± 3.78	125.8 ± 54.6
Clast (ng/mL)	0.31 ± 0.15	0.55 ± 0.26
Tlast (h)	8.00 ± 0.00	72.0 ± 0.00
Volume (L/kg)	0.20 ± 0.14	4.22 ± 2.07
Clearance (L/h/kg)	0.58 ± 0.21	0.90 ± 0.37
MRT (h)	2.27 ± 0.96	46.9 ± 14.5

All data reported as mean ± 1 SD.