Table 1.

Clinical statistics of the 512 ccRCC patients among the three subtypes in TCGA dataset. The p value was calculated by performing chi-square test or fisher test and further corrected by Bonferroni test

Clinical parameters	Molecular subtypes (n, %)			p value	FDR
	C1	C2	C3
Age
<60	99	121	22	0.3902838	0.4878548
≥60	116	138	16
T stage
T1-2	119	180	29	0.0015863	0.0044308
	T3-4	96	79	9
Race
White	194	234	25	0.0002154	0.0010770
Asian	4	2	2
Black or African American	17	23	11
Stage
Stage I	87	147	22	0.0017723	0.0044308
Stage II	24	26	6
Stage III	62	54	2
Stage IV	42	32	8
Radiation
Yes	2	3	0	0.7913667	0.7913667
NO	213	256	38
Pharmaceutical
Yes	32	34	7	0.644558	0.7161756
NO	183	225	31
Grade
G1	2	8	1	< 0.0001	< 0.0001
G2	77	129	13
G3	81	108	14
G4	54	14	5
GX	1	0	5
Smoking
1-year	106	131	28	0.1266751	0.2111252
2-year	13	9	3
3-year	80	97	6
4-year	11	14	1
5-year	5	8	0
Gender
FEMALE	51	112	13	4.90E-05	0.0004796
MALE	164	147	25
N
N0	91	115	22	0.03698	0.0739600
N1	11	3	2
NX	113	141	14
M
M0	163	215	28	0.1552	0.2217143
M1	41	30	7
MX	11	14	3