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. 2021 Mar 1;12(8):2430–2439. doi: 10.7150/jca.53385

Figure 6.

Figure 6

Depletion of circNT5E notably weaken the ability of Bca growth in vivo. (A) Subcutaneous tumor model demonstrated that the size of subcutaneous tumors derived from circNT5E depletion cells were obviously less than that collected from the negative control cells. (B) The size of subcutaneous tumors was calculated every 8 days. (C) The weight of subcutaneous tumors was evaluated after the mice were euthanized. (D) Depletion of circNT5E restrained HOXC8 expression and facilitated miR-502-5p expression in vivo. (E) The schematic of circNT5E/miR-502-5p/HOXC8 signal pathway. *P < 0.05, **P < 0.01 and NS: none significant.