Fig 4.

fMR images in a patient with a right meningioma. For this task, predominant activation typically is seen in the sensorimotor cortex of one hemisphere.

A, Image processed with reference function analysis. The patient moved the left hand according to the on-off commands; however, the patient moved the right hand when instructed to move right hand and when instructed to move the left hand. Therefore, this image shows anomalous activation.

B, However, the image processed with the ICA component specific for activation in the right hemisphere shows the expected unilateral activation pattern.