TABLE 1:
Results of cerebral MR imaging studies in 18 patients with SLS
| Patient | Sex | No. of Studies | Age Range, year | Myelin Deficit | Periventricular Zone of Abnormal Signal Intensity |
Atrophy | |
|---|---|---|---|---|---|---|---|
| Degree | Predominance | ||||||
| 1 | F | 3 | 0.8–1 | 1 | 1 | PO*† | 0 |
| 2 | M | 5 | 0.4–4 | 1 | 1 | PO | 0 |
| 3 | M | 2 | 3–5 | 1 | 1 | PO | 0 |
| 4 | M | 3 | 1–8 | 1 | 1 | PO | 0 |
| 5 | M | 1 | 8 | 1 | 1 | PO | 0 |
| 6 | M | 2 | 5–9 | 1 | 1 | PO | 0 |
| 7 | F | 2 | 6–9 | 1 | 1 | PO | 0 |
| 8 | M | 2 | 8–9 | 1 | 2 | FP* | 0 |
| 9 | F | 7 | 3–10 | 1 | 1 | PO | 0 |
| 10 | F | 1 | 10 | 1 | 1 | FP* | 1 |
| 11 | F | 1 | 13 | 1 | 1 | PO† | 0 |
| 12 | F | 3 | 11–14 | 1 | 1 | PO | 0 |
| 13 | M | 4 | 12–16 | 1 | 2 | FP | 1 |
| 14 | F | 3 | 12–17 | 1 | 1 | PO | 1 |
| 15 | F | 3 | 15–17 | 1 | 2 | FP*† | 0 |
| 16 | F | 3 | 16–21 | 1 | 1 | PO | 1 |
| 17 | M | 1 | 38 | 0 | 1 | PO | 1 |
| 18 | F | 2 | 41–45 | 1 | 1 | PO | 1 |
Note.—The results reflect findings from each patient’s latest MR imaging study. The degree of myelin deficit, periventricular signal-intensity abnormalities, and atrophy were scored as follows: 0 = none, 1 = mild, 2 = severe. PO = parieto-occipital, FP = frontoparietal.
*
Corpus callosum involved.
†
Patchy white matter lesions.