Table 2.
CNS Medication Class |
Controls, n = 1,264 |
Cases, n = 316 |
||
---|---|---|---|---|
n (%) | P-Value1 | |||
Antidepressant (serotonin norepinephrine reuptake inhibitor, selective serotonin reuptake inhibitor, tricyclic antidepressant) | 481 (38.1) | 112 (35.4) | .39 | |
Antiepileptic | 296 (23.4) | 74 (23.4) | >.99 | |
Antipsychotic | 296 (23.4) | 84 (26.6) | .24 | |
Benzodiazepine receptor agonist | 237 (18.8) | 70 (22.2) | .17 | |
Opioid receptor agonist | 427 (33.8) | 164 (51.9) | <.001 | |
Any CNS medication | 978 (77.4) | 254 (80.4) | .24 | |
Number of classes of CNS medications | .009 | |||
0 | 286 (22.6) | 62 (19.6) | ||
1 | 472 (37.3) | 95 (30.1) | ||
2 | 306 (24.2) | 92 (29.1) | ||
3–5 | 200 (15.8) | 67 (21.2) |
Conditional logistic regression model.