Fig 2.

Gross specimens obtained from the stillborn female neonate.

A, Frontal view of the brain shows a clear interhemispheric fissure extending to the rostral aspect of the frontal lobes. An abnormal transverse fissure can be seen extending into the dorsal midline of both hemispheres (arrowheads).

B, Coronal section at the level of the third ventricle demonstrates bilaterally symmetric, separated basal forebrain structures (hypothalamus, basal ganglia, and anterior thalamus). In contrast, the cerebral hemispheres are continuous across the dorsal midline with a mass of white matter and cerebral cortex crossing the dorsal midline with no clear corpus callosum.