TABLE 2:
ADC values in three patients with PBD and age-matched controls
| ADC values × 10−3 mm2/s | N | 12 Months |
16 Months |
80 Months |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient |
Control |
Diff. | % | Patient |
Control |
Diff. | % | Patient |
Control |
Diff. | % | |||
| Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |||||||||
| Genu of corpus callosum | 12 | 111 (7) | 107 (9) | 4 | 4 | 98 (8) | 75 (9) | 22 | 30‡ | 92 (10) | 69 (5) | 24 | 35‡ | |
| Splenium of corpus callosum | 12 | 115 (12) | 122 (23) | −7 | −6 | 98 (9) | 83 (7) | 15 | 18‡ | 110 (10) | 88 (16) | 22 | 25‡ | |
| Parietal corona radiata | R | 51 | 131 (7) | 106 (8) | 25 | 24‡ | 117 (5) | 102 (8) | 15 | 15‡ | 102 (7) | 93 (15) | 8 | 9‡ |
| L | 51 | 137 (5) | 108 (6) | 30 | 28‡ | 129 (7) | 109 (4) | 20 | 19‡ | 94 (8) | 91 (6) | 2 | 3* | |
| Frontal corona radiata | R | 51 | 127 (4) | 105 (6) | 23 | 22‡ | 115 (6) | 91 (5) | 24 | 27‡ | 94 (5) | 73 (5) | 20 | 28‡ |
| L | 51 | 124 (5) | 110 (11) | 14 | 13‡ | 114 (5) | 94 (4) | 21 | 22‡ | 92 (5) | 84 (5) | 8 | 10‡ | |
| Centrum semiovale | R | 51 | 131 (6) | 95 (3) | 35 | 37‡ | 106 (5) | 100 (5) | 6 | 6‡ | 100 (9) | 84 (6) | 16 | 20‡ |
| L | 51 | 141 (4) | 94 (5) | 47 | 49‡ | 110 (4) | 99 (5) | 11 | 11‡ | 95 (5) | 91 (9) | 4 | 4† | |
Note.—N indicates number of pixels per region of interest; significance determined with t test:
*
P < .05;
†
P < .01;
‡
P < .001.