Fig 1.

MR images obtained when the patient was 2 years 10 months old.

A, Axial fast spin-echo T2-weighted image (TR/TE, 3500/93; two signals acquired) at the level of the basal ganglia, showing diffuse demyelination involving mainly the frontal lobe sparing the occipital subcortical regions and internal capsule.

B, Coronal T1-weighted contrast-enhanced image (700/14), showing periventricular linear enhancement next to bilateral frontal horns.

C, Axial T1-weighted contrast-enhanced image (700/14), demonstrating enhanced lesions in bilateral globus pallidi (arrows).