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. 2021 Feb 8;17(3):834–847. doi: 10.7150/ijbs.57099

Figure 1.

Figure 1

AGR2 knockout reduces serum lipid levels and fat accumulation. The 8-week-old mice were fed a NCD or a HFD for an additional 10 weeks. A. Body weight of WT and Agr2-/- mice during the 10 weeks of NCD feeding (n=5). B. Body weight, fat mass, lean body mass and fat percentage of WT and Agr2-/- mice fed a NCD or a HFD (n=5). C. Body weight of WT and Agr2-/- mice during the 10 weeks of HFD feeding (n=5). D. Body weight of WT and Agr2/Tg mice during the 10 weeks of HFD feeding (n=5). E. Body weight, fat mass, lean body mass and fat percentage of WT and Agr2/Tg mice fed a HFD (n=5). F. Adipose tissue staining and the diameter of adipocytes in WT and Agr2-/- mice fed a NCD (top) or a HFD (bottom). G. Adipose tissue staining and the diameter of adipocytes in WT and Agr2/Tg mice fed NCD (top) or a HFD (bottom). H. Circulating lipid profiles of WT and Agr2-/- mice fed a NCD or a HFD (n=5). I. Circulating lipid profiles of WT and Agr2/Tg mice fed a NCD or a HFD (n=5). Representative figures were generated with data from at least three independent experiments. The data are presented as the mean ± SD values. *P < 0.05, **P < 0.01 by Student's t test.