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. 2021 Feb 8;17(3):834–847. doi: 10.7150/ijbs.57099

Figure 6.

Figure 6

AGR2 influences FA absorption in the intestine. The 8-week-old mice were fed a NCD or a HFD for an additional 10 weeks. A. Flow cytometric analysis of lipid absorption in SW480 cells treated with siRNA targeting AGR2. B. Flow cytometric analysis of lipid absorption in HT29 cells treated with AGR2 and AGR2-C81A expression plasmids. C. TG and TC contents in SW480 cells treated with siRNA targeting AGR2. D. TG and TC contents in HT29 cells treated with AGR2 and AGR2-C81A expression plasmids. E. Lipid absorption in WT and Agr2-/- mice fed a NCD or a HFD (n=5). F. Lipid absorption in WT and Agr2/Tg mice fed a NCD or a HFD (n=5). G. TG and TC contents in the intestines of WT and Agr2-/- mice fed a NCD or a HFD (n=5). H. TG and TC contents in the intestines of WT and Agr2/Tg mice fed a NCD or a HFD (n=5). I. Immunohistochemical staining of FA uptake proteins in the intestines of WT and Agr2-/- mice fed a NCD. J. Immunohistochemical staining of FA uptake proteins in the intestines of WT and Agr2/Tg mice fed a NCD. K. Immunofluorescence staining of CD36 and AGR2 in the intestines. Representative figures were generated with data from at least three independent experiments. The data are presented as the mean ± SD values. *P < 0.05 by Student's t test.