Fig 1.

An example of a ¹HMR spectroscopy study on a nonhuman primate 3 days after left hemispheric stroke (infarct volume, 15% of the hemisphere). A, Selected T2-weighted axial image with 2D MR spectroscopy overlay grid (FOV of the 2D-CSI dataset, 240 mm; 16 phase-encoding steps were acquired per side; section thickness, 15 mm; voxel cubic volume, 3.38 mL) demonstrates an intracerebral hyperintensity localized mainly to the anteromedial area of the left hemisphere, diagnostic for infarction. Remnants of the surgical approach to the circle of Willis are seen in the left orbit. Inside each voxel on the grid, the corresponding ¹H spectrum is shown after processing (see Methods). Spectra from the 4 highlighted voxels are expanded in B. Signal intensity assignments are shown on the expanded spectra, correlating with both normal and abnormal signals.