Sex, age |
Male, 1 year |
Female, 2 days |
Female, 1 day |
Female, 28 weeks’ gestation |
Female, 2 days |
Clinical presentation |
Macrocephaly, mild facial dysmorphism, developmental delay |
Protruding whitish mass from oral cavity |
Craniofacial deformity |
Prematurity, hydrocephalus with intraventricular hemorrhage on ultrasonogram |
Suspected choanal atresia |
Pituitary gland, duplicated pituitary and stalk |
Yes |
Yes |
Yes |
Yes |
Yes |
Hypothalamic thickening and tubomammillary fusion |
Yes |
Yes |
Yes |
Yes |
Yes |
Duplicated pituitary fossae and cleft basisphenoid |
Yes |
Yes |
Yes |
Yes |
Yes |
Sphenopharyngeal canal |
No |
Yes |
No |
Yes |
No |
Hypertelorism |
Yes |
Yes |
Yes |
Yes |
No |
Corpus callosum |
Normal |
Agenesis |
Agenesis |
Agenesis |
Normal |
Mouth and nasopharynx |
Normal |
Cleft palate, oral dermoid, frontonasal dysplasia |
Jaw teratoma, syngnathia, sphenomandibular-maxillary fusion, cleft palate |
Cleft palate |
Oral “hairy” dermoid, posterior cleft through bony palate |
Posterior fossa |
Wide pons, prominent ventral raphe |
Normal |
Normal |
Lower brain stem tethered anteriorly to pharynx through cleft above anterior arch of C1 with basion |
Lower brain stem tethered anteriorly to pharynx through cleft above anterior arch of C1 with basion |
Basilar artery |
Duplicated, MR angiogram available |
Duplicated, only spin-echo images available |
Duplicated, only spin-echo images available |
Duplicated, MR angiogram available |
Duplicated, MR angiogram available |
Cervical spine anomalies/anomalies of basion |
Yes |
Yes |
Yes |
Yes |
Yes |