TABLE 1:
Participant clinical data and position emission tomography hemodynamic parameters
| Participant | Age/Sex/Handedness | Side of Occlusion | Clinical History | PET |
|||
|---|---|---|---|---|---|---|---|
| CBF | CBV | MTT | OEF | ||||
| 1 | 67/M/R | L | Asymptomatic | 0.85 | 0.89 | 1.05 | 1.02 |
| 2 | 65/F/R | L | Asymptomatic | 0.84 | 0.95 | 1.13 | 1.03 |
| 3 | 58/M/R | L | Left parietal infarct | 0.89 | 1.30 | 1.46 | 1.09 |
| 4 | 67/M/L | L | Left posteriorfrontal infarct | 0.87 | 1.10 | 1.26 | 0.93 |
| 5 | 71/M/R | R | Asymptomatic | 0.96 | 1.13 | 1.17 | 0.98 |
| 6 | 76/M/R | R | Right posterior parietal infarct | 0.98 | 1.17 | 1.19 | 1.04 |
| 7 | 65/M/R | L | Left frontoparietal infarct | 0.80 | 1.09 | 1.37 | 1.06 |
All positron emission tomography hemodynamic parameters are ipsilateral-to-contralateral ratios of mean hemispheric values. Cerebral blood volume, mean transit time, and oxygen extraction fraction ratios that exceed the range observed in 18 normal control participants are shown in bold text. The upper limits for normal hemispheric ratios for cerebral blood volume, mean transit time, and oxygen extraction were 1.21, 1.14, and 1.08, respectively. Hemodynamic impairment is clearly shown for participant 3. Participants 4 through 7 may have some degree of autoregulatory vasodilation, with elevated mean transit times.
Note.—PET indicates positron emission tomography; CBF, cerebral blood flow; CBV, cerebral blood volume; MTT, mean transit time; OEF, oxygen extraction fraction; M, male; F, female; R, right; L, left.