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Signaling pathways and drug targets.
AC: Adenyl cyclase; cAMP: Cyclic adenosine monophosphate; AKT: Protein kinase B; GPCR: G-protein coupled receptor; GTP: Guanosine Triphosphate; MEK: Mitogen-activated protein kinase; ERK: extracellular signal-regulated kinase; mTOR: Mammalian target of rapamycine; PI3K: Phosphoinositide 3-kinase; RAF: Rapidly Accelerated Fibrosarcoma; RAS: Rat Sarcoma protein; R-TK: Receptor Tirosyne Kinase
