Table 3.
Multivariable Cox hazards analysis of colorectal cancer patients. The multivariable Cox hazards analysis model initially included sex, age, tumor size, primary tumor location, pT stage, tumor histology, mucus production, lymph node metastasis, peritoneal metastasis, distant organ metastasis, operation status, mismatch-repair system status, and immunohistochemistry for CD47, SIRPA, CD68, and CD163. A backward elimination with a threshold of p = 0.05 was used to select variables in the final model. TAIs, tumor-associated inflammatory cells.
| 95% CI | ||||
|---|---|---|---|---|
| HR | Min | Max | p-Value | |
| Well to moderately differentiated histology | 0.23 | 0.12 | 0.42 | <0.0001 |
| Age (<70) | 0.48 | 0.27 | 0.82 | 0.0087 |
| TAIs SIRPA High | 0.55 | 0.32 | 0.93 | 0.027 |
| Tumor CD47 High | 1.75 | 1.03 | 2.98 | 0.038 |
| Lymph node metastasis | 2.26 | 1.31 | 3.91 | 0.0036 |
| Peritoneal metastasis | 5.80 | 3.23 | 10.43 | <0.0001 |