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. 2005 Oct;26(9):2275–2281.

TABLE 2:

FA and ADC measurements in all four locations in HIV-positive patients and controls according to the viral load in plasma

Controls(n = 16) HIV+ Patients: Viral Load (Copies/mL)
<50 (n = 12) P Value 50–100 000 (n = 19) P Value >100 000 (n = 22) P Value
Splenium FA 753 ± 56 770 ± 92 791 ± 80 755 ± 63 NS
Genu FA 717 ± 68 680 ± 54 679 ± 68 679 ± 93 NS
White matter FA 404 ± 52 367 ± 35 381 ± 39 402 ± 50 NS
Hippocampus FA 366 ± 65 364 ± 101 350 ± 54 357 ± 46 NS
Splenium ADC 858 ± 114 942 ± 155 .023 836 ± 96 NS 858 ± 72 NS
Genu ADC 1054 ± 146 1286 ± 255 NS 1135 ± 192 NS 1159 ± 208 NS
White matter ADC 792 ± 44 851 ± 70 .028 807 ± 42 NS 796 ± 57 NS
Hippocampus ADC 968 ± 129 1081 ± 189 NS 1018 ± 123 NS 1029 ± 122 NS

Note.—FA indicates fractional anisotropy; ADC, apparent diffusion coefficient (mm/s2); NS, not significant.