TABLE 2:

Item-by-item intraclass correlation (ICC) values for interobserver and intraobserver agreement

Feature	Interobserver Agreement	Intraobserver Agreement
Lateral ventricle
Blunting of lateral angles of midpoint of body of lateral ventricles	0.95	0.90
Blunting of lateral angles of frontal horns of lateral ventricles	0.91	0.85
Enlargement of frontal horns of lateral ventricles	0.79	0.62
Enlargement of body of lateral ventricles	0.80	0.62
Enlargement of occipital horns of lateral ventricles	0.57	0.82
Asymmetry of lateral ventricle	0.75	0.91
Abnormal shape of lateral ventricle	0.47	0.80
Third ventricle
Widening of anterior portion of third ventricle	0.74	0.52
Widening throughout third ventricle	0.77	0.52
Cortex
Enlargement of cortical sulci	0.58	0.75
Enlargement of subarachnoid spaces	0.64	0.83
Enlargement of interhemispheric fissure	0.51	1
Enlargement of subarachnoid cisterns	0.54	0.73
Temporal lobe
Abnormal shape of hippocampus	0.82	1
Abnormal gyral pattern of hippocampus	0.72	1
Reduced size of hippocampus	0.65	1
Enlargement of temporal horns	0.61	0.90
White matter abnormalities
Corpus callosal thinning	0.75	0.90
Corpus callosal notching	0.72	0.89
Focal high-intensity white matter lesions	0.51	0.94
White matter volume loss	0.68	1
Virchow-Robin spaces	0.55	0.73
Other abnormalities
Cavum septi pellucidi or cavum vergae	0.70	—*
Arachnoid cysts	0.94	1
Cerebellar tonsil through occipital foramen	0.87	0.85
Enlarged cisterna magna	0.69	0.58
Total abnormality score	0.93	0.97

Note.—This table excludes 10 items for which the observed frequency was <2% in 120 scans.

*ICC could not be calculated due to 0 variance within one set of observations.