TABLE.

Cross-Sectional Age-Related Differences in Striatal Volumes Measured Five Years Apart

Nucleus	Raw Volume						Regression of ICV-Adjusted Volume on Age						r12
	Time 1			Time 2			Time 1			Time 2
	Mean	SD	CV	Mean	SD	CV	Slope	SE	rage	Slope	SE	rage
Caudate	9.42	1.14	0.12	9.00	1.09	0.12	−.031	.010	−.41	−.034	.009	−.47	.95
Putamen	10.41	0.98	0.09	10.01	1.02	0.10	−.030	.008	−.46	−.033	.008	−.49	.89
Globus Pallidus	2.16	0.27	0.12	2.10	0.27	0.13	.004	.002	.22	.004	.002	.21	.93

Note.—CV (coefficient of variation) is a ratio of standard deviation (SD) to the mean. The regression slopes are unstandardized regression coefficients measured in cc/year. SE is standard error of slope. All coefficients for the caudate nucleus and putamen are significantly different from zero, whereas those for the globus pallidus are not. The differences in slopes between the neostriatum (caudate and putamen) and paleostriatum are statistically significant (p < .05). Correlations are Pearson product moment coefficients. All correlations r > .23 are significantly different from zero.