Table III.
The rs1048990 alleles and genotypes presentation in responders and non-responders to IFNβ therapy.
| IFN-β (n) | Statistics | ||||
|---|---|---|---|---|---|
| Allele or genotype | R | NR | Model | P-value | OR [95% CI] |
| C | 70 (94.59) | 194 (87.39) | G vs. C | 0.059 | 2.53 [0.90-7.08] |
| G | 4 (5.41) | 28 (12.61) | G vs. CC | 0.056 | 2.69 [0.92-7.84] |
| CC | 33 (89.19) | 86 (77.48) | - | - | - |
| CG | 4 (10.81) | 22 (19.82) | CG + GG vs. CC | 0.090 | 2.40 [0.78-7.42] |
| GG | - | 3 (2.70) | - | - | - |
The numbers of alleles and genotypes (in brackets, frequency in percent) in the groups of study participants are presented as n (%). R, responders; NR, non-responders; IFN-β, interferon β; OR, odds ratio; CI, confidence interval.