TABLE 1:
Timing parameters from the myelination model
| Region | Onset (months) |
TC (months) |
Maturation Age (months) |
|||
|---|---|---|---|---|---|---|
| 18q− | Control | 18q− | Control | 18q− | Control | |
| FWM | 6.7 ± 0.54 | 1.8 ± 1.03 | 16.3 ± 2.54 | 10.3 ± 0.30 | 71.9 ± 10.17 | 43.2 ± 1.59 |
| SWM | 3.6 ± 0.94 | 0.8 ± 0.16 | 12.4 ± 0.95 | 6.3 ± 0.75 | 53.2 ± 3.93 | 26.0 ± 3.02 |
| PWM | 3.7 ± 1.75 | 1.9 ± 0.25 | 12.7 ± 3.59 | 8.2 ± 0.93 | 54.5 ± 14.40 | 34.7 ± 3.74 |
| Genu | 2.6 ± 1.10 | 1.9 ± 0.51 | 13.1 ± 0.57 | 5.4 ± 0.27 | 55.0 ± 2.54 | 23.5 ± 1.18 |
| Splenium | 3.1 ± 0.45 | 2.3 ± 0.11 | 8.1 ± 2.44 | 2.4 ± 0.47 | 35.5 ± 9.77 | 11.9 ± 1.90 |
| MCBP | −4.9 ± 0.49 | −3.9 ± 0.60 | 12.1 ± 2.87 | 4.1 ± 0.47 | 43.5 ± 11.50 | 12.5 ± 1.97 |
Note.—TC is the time constant for myelination model; maturation age, Age when myelin development reaches about 98% of the equilibrium level (onset + 4TC). All SDs estimated by using propagation of errors from Bevington et al (24).