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. 2020 Dec 11;137(11):1449–1456. doi: 10.1182/blood.2020007225

Table 3.

SIR and AER of SMNs

Cancer diagnosis Observed cases Expected cases SIR 95% CI AER
Any SMN 17 1.79 9.5 4.5-15.2 1.2
Solid tumor within RT field* 10 0.1 105.1 83.2-193.4 0.8
MDS/AML 3 0.012 249.9 195.7-730.3 0.2
NHL 2 0.02 94.4 63.7-340.9 0.2
Osteosarcoma 1 0.068 14.7 5.5-81.9 0.1
Embryonal carcinoma 1 0.027 37.4 17.9-207.8 0.1
Papillary thyroid carcinoma 6 0.06 100.1 76.9-217.8 0.5
Mucoepidermoid carcinoma 1 0.008 119.4 68.1-664.5 0.1
Renal cell carcinoma 1 0.005 207.4 124.5-1153.7 0.1
Breast cancer 1 0 NA NA 0.1

MDS, myelodysplastic syndromes; NA, not applicable.

*

Solid tumors within the RT field for this cohort included osteosarcoma, papillary thyroid carcinoma, mucoepidermoid carcinoma, and breast cancer.