Fig 4.

Extrapolation from our dataset to high b values yielded mean displacement and probability of zero-displacement plots.

A, Plot shows the transient decrease in mean proton displacement after seizure-induced injury. A moderate decrease is evident in the mean diffusion distance that returns to control levels by 7 days.

B, Similarly, the probability of a proton having zero displacement after seizure induction rapidly and markedly decreases at 12 hours. By 24 hours, this rebounds, indicating transient changes in the tissue matrix in the piriform cortex. By 7 days, the probability of zero displacement is reduced compared with that in control animals. Together, these extrapolation parameters support tissue remodeling that occurs as result of seizure-induced lesions.