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. 2021 Feb 6;18(7):1670–1679. doi: 10.7150/ijms.54460

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Hub genes analysis. (A) The 25 most important hub genes selected by connectivity degree were screened out using the cytoHubba. The color of node from yellow to red represented the connectivity degree from low to high. (B) The KEGG analysis of hub genes was performed using the ClueGO and the CluePedia. Different color of node denoted different functional annotation of ontology. (C) The GO analysis of hub genes was performed using the ClueGO and the CluePedia. Different color of node denoted different functional annotation of ontology.