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. 2021 Feb 18;18(8):1768–1777. doi: 10.7150/ijms.54655

Table 5.

The association between obesity or overweight and severity, organ damage, or endpoint in patients with COVID-19

Odd Ratio 95% CI P value
Critical illness
Model 1
Normal - - -
Overweight 1.250 0.650-2.401 0.504
Obesity 2.105 0.833-5.317 0.116
Model 2
Overweight 1.240 0.629-2.445 0.534
Obesity 1.973 0.744-5.231 0.172
Severe + Critical illness
Model 1
Overweight 1.409 0.944-2.104 0.093
Obesity 3.096 1.376-6.970 0.006*
Model 2
Overweight 1.443 0.953-2.185 0.083
Obesity 3.586 1.550-8.298 0.003*
Organ damage
Model 1
Overweight 0.872 0.485-1.570 0.649
Obesity 2.051 0.920-4.571 0.079
Model 2
Overweight 0.894 0.490-1.634 0.716
Obesity 2.005 0.875-4.593 0.100
Endpoint
Model 1
Overweight 1.250 0.650-2.401 0.504
Obesity 1.422 0.505-4.006 0.505
Model 2
Overweight 1.231 0.622-2.434 0.551
Obesity 1.299 0.440-3.838 0.636

Endpoint was a composite of mechanical ventilation or admission of intensive care unit, after all patients were followed for 30 days. Model 1: Univariate regression analysis. Model 2: Multivariate regression analysis with adjusting for sex, age and comorbidities (e.g. hypertension, diabetes, coronary artery disease, arrhythmia, cerebrovascular disease, COPD, asthma, chronic renal disease and chronic liver disease).