Figure 2.

Forest plots of the concentration of healthy subjects of HMGB1 in the upper and lower airways. (A) Plot for HMGB1 in the upper and lower airways. (B) Plot for sensitivity analysis, excluding one study at a time, for HMGB1 in the upper and lower airways. (C, D) Plots for HMGB1 in the (C) lower and (D) upper airways. The figure depicts individual trials as filled squares with sizes relative to the sample size and the 95% confidence interval of the difference as the solid line. The diamond shape indicates the pooled estimate and uncertainty for the combined effect.