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Binding interactions of selected drugs with SARS-CoV-2 spike glycoprotein. (A) chloroquine closed state, (B) chloroquine open state, (C) hydroxychloroquine closed state, (D) hydroxychloroquine, open state, (E) ivermectin closed state, (F) ivermectin, open state (G) remdesivir closed state, (H) remdesivir, open state, (I) favipiravir, closed state, (J) favipiravir, open state.
