fig 2.

Case 2.

A, Unenhanced CT scan at age 3 months shows the supratentorial white matter is probably slightly hypodense, especially in the paraventricular and subcortical regions; however, swelling is not particularly pronounced in this case. Both the ventricles and the subarachnoid spaces are slightly dilated, consistent with immaturity of CSF absorption at this age.

B–D, Axial T2-weighted (B), axial fluid-attenuated inversion-recovery (C), and sagittal T1-weighted (D) MR images at 7 years show marked and diffuse bulk loss in the supratentorial white matter; the cortex nearly abuts on the ventricular surface. Slight residual hyperintensity is seen in the periventricular regions, especially posterior to the left trigone (arrowheads, B and C). The basal ganglia are spared, and the lateral ventricles are slightly enlarged ex-vacuo. Notice marked, diffuse thinning of the corpus callosum (arrows, D).